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About Spravato
We provide Spravato® (esketamine) treatment in Houston, TX for adults struggling with treatment-resistant depression. Our board-certified psychiatric clinic offers evidence-based care with rapid scheduling and insurance coordination.
Spravato® therapy is one of the most advanced options available today for individuals with treatment-resistant depression in Houston who have not responded to standard oral medications. Esketamine works on the glutamate neurotransmitter pathway, helping restore neural connections believed to be impaired in major depressive disorder.
Treatment sessions occur onsite with medical monitoring lasting approximately two hours. Patients typically begin with twice-weekly sessions for the first four weeks, followed by weekly or biweekly maintenance treatments according to clinical response.
Benefits of Spravato Therapy
• Rapid symptom reduction compared to traditional antidepressants
• Effective for depression resistant to multiple prior medications
• Non-invasive nasal administration
• Close psychiatric supervision for safety
Cost & Insurance for Spravato in Houston
Insurance coverage varies by provider, but most plans reimburse Spravato therapy once FDA criteria are met. Our team provides:
✅ Prior Authorizations
✅ Benefits verification
✅ Co-pay estimates
✅ Out-of-pocket programming if needed
We accept Medicare and most major commercial plans.
How to Start Spravato Treatment
1️⃣ Schedule a psychiatric consultation
2️⃣ Complete eligibility screening
3️⃣ Insurance verification & prior authorization
4️⃣ Begin supervised Spravato sessions
Our clinic works to minimize administrative delays so patients may start with same-week or next-week appointments when clinically appropriate.

Frequently asked questions
Who qualifies for Spravato treatment in Houston?
Adults with treatment-resistant depression who have tried at least two antidepressant medications and remain symptomatic are typically eligible after formal psychiatric evaluation.
Is Spravato covered by insurance in Texas?
Many major plans including BCBS, UHC, Medicare, Cigna, Tricare, Humana, Ambetter, as well as several Pharmacy Benefit Managers
What is the cost of Spravato treatment in Houston?
Costs depend on insurance coverage and copay structure. Our office verifies benefits beforehand to provide transparent pricing estimates. The cost varies upon which insurance you carrry but there is a Spravato Savings Program with SPRAVATO withMe
Is Spravato safer than ketamine infusions?
Spravato is FDA-approved and administered only in medical settings under REMS monitoring requirements, providing a standardized safety framework.
Is Spravato treatment right for me?
Spravato (esketamine) has been found to be useful for patients who have not experienced full relief of depression from at least two traditional antidepressant medications. Prior to being scheduled for Spravato, your provider will give you a full psychiatric evaluation to determine if you qualify for esketamine treatment.
What should I expect the day of my treatment?
You will be monitored very closely during your Spravato treatment. This will include blood pressure, pulse measurements, and some psychological measurements before and after your session.
How does it work?
A low dose of Spravato will be administered via intra-nasal spray. After five minutes another small dose will be administered. Your provider will monitor you for a two hour waiting period. We encourage you to wear eye shades, listen to relaxing music, and focus inward during this time
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Does it have any side effects?
Spravato's side effects wear off quite quickly; you will be able to return home about 2 hours after treatment is complete. Patients are required to have another person drive them home. You should not drive until the next day after a restful sleep.
During treatment, patients may experience an altered or dream like state, which most describe as very pleasing..
What to expect:
The practitioner will administer each dose five minutes apart and check on you once during the process. Please be aware that no special services will be provided. In our clinic we have changed to a more medical and sterile setting.
Our Spravato staff is under new management so please be prepared for new changes.
If you would like our patient coordinator to contact you to schedule a NEW PATIENT appointment please fill out the form found in the link below and submit. Our patient coordinator will contact you from the number 832-538-1479.
Patient Testimony
"Referred here for Spravato Treatment and definitely has been for the best! Elizabeth is who I worked with here and she was very helpful and informative through the whole process."
Patient Testimony
"Was very easy to contact and arrange an appointment. Staff was professional and courteous. I really appreciate the way I was/am treated there. I feel that my concerns are listened to and addressed. I have not had any problems with wait times. I found that he and his office work well with other doctors."
Patient Testimony
"Dr. Leesem is an excellent and knowledgeable physician. During my first visit I was actually nervous and didn't know what to expect. As I begin to talk with him, I noticed he was very empathic and totally understood what I was experiencing. He actually listened to me. I immediately began to be comfortable talking with him. He spoke to me very compassionately. He start a plan of care for me and scheduled regular visits to treat me. I must say this is the best I have felt in years. I respect and value his opinion. I owe it all to this good natured kind hearted man. He definitely cares about his patients."